CCM Seminar: Pilar Cossio (CCM)

Wednesday Oct 20, 2021, 10:00 AM → 11:15 AM America/New_York

3rd floor classroom

Title: SMBp research topics and transition rates from biased simulations

Abstract: In this talk, first, I will present an overview of the research problems of the structural and molecular biophysics group. Then, I will present a methodology, inspired by single-molecule force spectroscopy, and based on Kramers' theory for calculating the barrier-crossing rate when a time-dependent bias is added to a system. I will present approximate analytical expressions of the survival probability that accurately reproduce the barrier-crossing time statistics, and enable the extraction of the unbiased transition rate even for challenging cases, where previous methods fail.

If you would like to attend, please email crampersad@flatironinstitute.org for the Zoom link.