Speaker
William Leeb
(University of Minnesota)
Description
We will present recent work on the problem of simultaneously denoising cryo-EM images and correcting for the effects of the contrast transfer function (CTF). The methods used are based on new results from high-dimensional principal component analysis and matrix recovery in the spiked covariance model. We use new spectral shrinkers that account for the effects of both the CTF and the colored noise distribution. This is joint work with Joakim Andén and Amit Singer.
Primary author
William Leeb
(University of Minnesota)
