NYC Computational Cryo-EM Summer Workshop

Session

Chair: Amit Singer

Aug 8, 2019, 9:10 AM

Ingrid Daubechies Auditorium (Flatiron Institute)

6. Joachim Frank; Mapping of conformational states of macromolecules

Dr Joachim Frank

8/8/19, 9:10 AM

The ability of single-particle cryo-EM to furnish hundreds of thousand images of molecules fast-frozen in solution means that even rarely sighted conformations, corresponding to high-energy states, are represented in the data set. As a consequence, a continuum of states is experimentally accessible (Frank, Biochemistry 2018). Current practice of cryo-EM structure research does not take...

10. Bridget Carragher; CryoEM and CryoET: A brief intro and some thoughts about future computational needs

Dr Bridget Carragher

8/8/19, 9:50 AM