NYC Computational Cryo-EM Summer Workshop

Session

Chair: Fred Sigworth

Aug 8, 2019, 3:50 PM

Ingrid Daubechies Auditorium (Flatiron Institute)

12. Alberto Bartesaghi; Data-driven Strategies for Unsupervised Single-particle Reconstruction

Dr Alberto Bartesaghi

8/8/19, 3:50 PM

Automated protocols for data acquisition used in modern cryo-EM facilities combined with the newer generation of larger and faster cameras have dramatically increased the throughput of data collection, exacerbating the need to develop effective strategies for structure determination that can operate without a user in the loop in order to keep up with the rate of data production. I’ll present...

13. Richard Henderson; Getting the most out of cryo-EM images

Dr Richard Henderson

8/8/19, 4:30 PM

Single particle cryo-EM images are still not perfect. I will discuss some work that Chris Russo and I have done recently to identify the remaining sources of imperfection and what might be done either by computation or by experimentation to overcome these problems.