3D Nucleome Workshop

America/New_York
3rd Floor Classroom (Flatiron Institute)

3rd Floor Classroom

Flatiron Institute

162 Fifth Avenue New York, NY 10010
Mike Shelley, Olga Troyanskaya
Description

The Center for Computational Biology at the Flatiron Institute in New York City will hold a two-day workshop, "The 3D Nucleome", intended to bring together researchers working in sometimes separated domains of study of the nucleus.

These domains include biophysics, computational biology, mathematical modeling, epigenomics, genetics, and molecular biology. We are hoping for an intimate environment that encourages the free exchange of ideas and discussions of ongoing work.

  • Wednesday, 7 August
    • 08:00 08:45
      BREAKFAST 45m 3rd Floor ()

      3rd Floor

    • 08:45 09:00
      Welcome Remarks by Mike Shelley 3rd Floor Classroom

      3rd Floor Classroom

      Flatiron Institute

      162 Fifth Avenue New York, NY 10010
    • 09:00 09:45
      Mechanics, topology and geometry of mammalian chromosomes and nuclei

      John Marko, Northwestern University

    • 10:15 11:00
      Cracking the Nuclear Codes: Finding Order in Chaos

      Clodagh O'Shea, Salk Institute

    • 11:00 11:30
      BREAK 30m 3rd Floor

      3rd Floor

    • 11:30 12:15
      The mechanical genome

      Helmut Schiessel, Leiden University

    • 12:30 13:30
      LUNCH 1h 2nd Floor Promenade

      2nd Floor Promenade

      Flatiron Institute

    • 13:30 14:15
      Disentangling the spatial and temporal dynamics of epigenetic domains in single cells

      Bassem Al-Sady, University of California, San Francisco

    • 14:30 15:15
      Reconstitution of basic chromatin processes in cell free extracts: loop extrusion and DNA wetting

      Jan Brugues, Max Planck Institute

    • 15:30 16:00
      BREAK 30m 3rd Floor

      3rd Floor

    • 16:00 16:45
      Detection of multiple levels of chromatin organization by TrAC-looping

      Keji Zhao, National Institutes of Health

    • 17:00 17:45
      Large-scale numerical simulations of interphase chromatin hydrodynamics 3rd Floor Classroom

      3rd Floor Classroom

      Flatiron Institute

      162 Fifth Avenue New York, NY 10010

      David Saintillan, University of California, San Diego

    • 18:30 21:30
      DINNER 3h

      Benno Restaurant
      Evelyn Hotel
      7 E 27th Street

  • Thursday, 8 August
    • 08:30 09:00
      BREAKFAST 30m 3rd Floor

      3rd Floor

    • 09:00 09:45
      The "self-stirred genome": dynamics and rheology

      Alexandra Zidovska, New York University

    • 10:00 10:45
      Chromatin domains in transcriptional regulation

      Bing Ren, University of California, San Diego

    • 11:00 11:30
      BREAK 30m 3rd Floor

      3rd Floor

    • 11:30 12:15
      Two major mechanisms of chromosome organization

      Leonid Mirny, Massachusetts Institute of Technology

    • 12:30 13:30
      LUNCH 1h 3rd Floor Lounge

      3rd Floor Lounge

    • 13:30 14:15
      Acidity and hydrophobicity in transcription factor activation domains

      Max Staller, Washington University St. Louis

    • 15:00 15:45
      Genomes in 3D: connections between structure and function

      Geoff Fudenberg, University of California, San Francisco

    • 16:00 18:00
      RECEPTION 2h 3rd Floor Lounge

      3rd Floor Lounge