CCB Colloquium: Raymond Goldstein, University of Cambridge

You are cordially invited to the Center for Computational Biology Colloquium 
Tuesday, November 2, 2021
10:00am ET
Virtual 

Presenter: 
Professor Raymond E. Goldstein, FRS
Schlumberger Professor of Complex Physical Systems
Department of Applied Mathematics and Theoretical Physics
Centre for Mathematical SciencesUniversity of Cambridge

Topic: Cytoplasmic Streaming and the Swirling Instability of the Microtubule Cytoskeleton

Cytoplasmic streaming is the persistent circulation of the fluid contents of large eukaryotic cells, driven by the action of molecular motors moving along cytoskeletal filaments, entraining fluid. Discovered in 1774 by Bonaventura Corti, it is now recognized as a common phenomenon in a very broad range of model organisms, from plants to flies and worms. This talk will discuss physical approaches to understanding this phenomenon through a combination of experiments (on aquatic plants, Drosophila, and other active matter systems), theory, and computation. A particular focus will be on streaming in the Drosophila oocyte, for which I will describe a recently discovered "swirling instability" of the microtubule cytoskeleton.